Article

Collaborative study of thresholds for mutagens: Hormetic responses in the micronucleus test and gene induction by mutagenic treatments

2023-11-16

Abstract excerpt

The linear no-threshold model (LNT) asserts that the genetic effects and carcinogenicity of radiation are proportional to the dose. LNT is also applied to carcinogens and mutagens. However, most experimental data show that the dose-response curve is not linear but rather a J-shaped curve, known as a hormetic response. LNT and hormesis are mutually exclusive. Which is correct? In this study, we investigated dose-re...

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Literature Corpus work: 8f5ee1f5-5f32-5748-8730-3d56bc382550
DOI: 10.21203/rs.3.rs-3550460/v1

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