Article
The problem of extrapolating from observed carcinogenic effects to estimates of risk for exposed populations.
Journal of toxicology and environmental health - 1 Jan 2000
Saffiotti U
Abstract excerpt
A review is presented of the complex problems involved in the quantitative estimation of cancer risk for populations exposed to carcinogens on the basis of evidence provided either by epidemiologic studies or by experimental data. Strain and species differences among experimental animals and wide interindividual differences among human subjects are discussed. Examples from quantitative laboratory studies on...
Topics
- Carcinogens
- Cells, Cultured
- Humans
- Legislation, Drug
- Models, Biological
- Mutation
- Neoplasms
- Probability
- Risk
- Statistics as Topic
- United States
