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Article

Integrated p53 histopathologic/genetic analysis of premalignant lesions of the esophagus.

Cancer detection and prevention - 1 Jan 2000

Safatle-Ribeiro A V, Ribeiro U, Sakai P, Clarke M R, Fylyk S N, Ishioka S, Gama-Rodrigues J, Finkelstein S D, Reynolds J C

Abstract excerpt

UNLABELLED: Esophageal carcinoma frequently occurs in patients with long-standing achalasia. AIM: To examine the role of p53 alterations and PCNA in patients with megaesophagus. METHODS: Sections of four tumors, and corresponding adjacent areas, from patients with achalasia due to Chagas' disease were examined by immunohistochemistry for p53 and PCNA proteins. Furthermore, 128 biopsies from 16 advanced achalasic...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10757119

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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