Article
[P53-status in primary ovarian carcinomas, ovarian metastases of neoplasms in other sites and benign ovarian tumors: predictive value in comparison to histopathological parameters].
Zentralblatt fur Gynakologie - 1 Jan 2000
Casper F, Weikel W, Schaffrath M, Kuner R P, Hoffmann G, Pollow B, Pollow K
Abstract excerpt
OBJECTIVE: The purpose of this study was to determine whether the tumor suppressor gene p53 can be used as a prognosis factor to assess individual patient risk in primary ovarian carcinoma. MATERIALS AND METHODS: The concentration of the mutated, as well as the wild type p53 was examined in 98 cases of ovarian carcinoma. Among 98 ovarian tumors examined, 77 were primary carcinomas, 14 tumors were metastasis of...
Topics
- Age Factors
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Carcinoma
- Enzyme-Linked Immunosorbent Assay
- Female
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Humans
- Life Expectancy
- Middle Aged
- Mutation