Article
p53 as a prognostic factor for stage III serous adenocarcinoma of the ovary.
Anticancer research - 1 Jan 2000
Daponte A, Guidozi F, Tiltman A J, Marineanu A, Taylor L
Abstract excerpt
Expression of mutant p53 in 19 patients with stage III moderately differentiated serous cystadenocarcinoma of the ovary, who all had optimal primary cytoreductive surgery and six cycles of cisplatin and cyclophosphamide was analyzed to determine its prognostic significance. All patients were followed up for a minimum of 48 months. Immunohistochemical analysis for mutant p53 was by means of monoclonal antibody DO7...
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