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Article

Highly resistant Burkholderia pseudomallei small colony variants isolated in vitro and in experimental melioidosis.

Medical microbiology and immunology - 1 Nov 1999

Häussler S, Rohde M, Steinmetz I

Abstract excerpt

Burkhloderia pseudomallei is the causative agent of melioidosis, a disease in which treatment failures and relapses are common. This study reports on slow growing B. pseudomallei 'small colony variants' (SCVs), isolated either in vitro after exposure to ceftazidime, ciprofloxacin or gentamicin or from the spleen and liver in a mouse model of melioidosis after treatment with ceftazidime. Interestingly, SCVs...

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Identifiers

PMID: 10753061
DOI: 10.1007/s004300050110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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