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Article

Alteration of the phenotypic and pathogenic patterns of Burkholderia pseudomallei that persist in a soil environment.

The American journal of tropical medicine and hygiene - 1 Mar 2014

Chen Yao-Shen, Shieh Wun-Ju, Goldsmith Cynthia S, Metcalfe Maureen G, Greer Patricia W, Zaki Sherif R, Chang Hsin-Hou, Chan Hao, Chen Ya-Lei

Abstract excerpt

Melioidosis is caused by the soil-borne pathogen Burkholderia pseudomallei. To investigate whether the distinct phenotypic and virulent characteristics result from environmental adaptations in the soil or from the host body, two pairs of isogenic strains were generated by passages in soil or mice. After cultivation in soil, the levels of 3-hydroxytetradecanoic acid, biofilm formation, flagellar expression, and...

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Identifiers

PMID: 24445207
DOI: 10.4269/ajtmh.13-0051
PMCID: PMC3945693

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Source receipt: pubmed, retrieved 7 Sept 2026.

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