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Article

Characterization of in vitro phenotypes of Burkholderia pseudomallei and Burkholderia mallei strains potentially associated with persistent infection in mice.

Archives of microbiology - 1 Mar 2017

Bernhards R C, Cote C K, Amemiya K, Waag D M, Klimko C P, Worsham P L, Welkos S L

Abstract excerpt

Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm), the agents of melioidosis and glanders, respectively, are Tier 1 biothreats. They infect humans and animals, causing disease ranging from acute and fatal to protracted and chronic. Chronic infections are especially challenging to treat, and the identification of in vitro phenotypic markers which signal progression from acute to persistent infection...

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PMID: 27738703
DOI: 10.1007/s00203-016-1303-8
PMCID: PMC5306356

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