Article
Microevolution of Burkholderia pseudomallei during an acute infection.
Journal of clinical microbiology - 1 Sept 2014
Limmathurotsakul Direk, Holden Matthew T G, Coupland Paul, Price Erin P, Chantratita Narisara, Wuthiekanun Vanaporn, Amornchai Premjit, Parkhill Julian, Peacock Sharon J
Abstract excerpt
We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei after inoculation and systemic spread.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
