Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye.

Development (Cambridge, England) - 1 May 2000

Winkler S, Loosli F, Henrich T, Wakamatsu Y, Wittbrodt J

Abstract excerpt

In early vertebrate eye development, the retinal anlage is specified in the anterior neuroectoderm. During neurulation, the optic vesicles evaginate from the lateral wall of the prosencephalon. Here we describe the temperature-sensitive mutation eyeless in the Japanese medakafish. Marker gene analysis indicates that, whereas, specification of two retinal primordia and proximodistal patterning takes place in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Eye
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Morphogenesis

Share to Oryzias

Share to Paired Box Transcription Factors

Share to PAX6 Transcription Factor

Share to Retina

Source

Identifiers

PMID: 10751179
DOI: 10.1242/dev.127.9.1911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The conditional medaka mutation eyeless uncouples patterning and morphogenesis of the eye.PMID 10751179Read ↗

Medaka eyeless is the key factor linking retinal determination and eye growth.Semantic proximity Read ↗

Brain structures of a medaka mutant, el (eyeless), in which eye vesicles do not evaginate.Semantic proximity Read ↗

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila.Semantic proximity Read ↗

Regulation of vertebrate eye development by Rx genes.Semantic proximity Read ↗

Mutational analysis of the eyeless gene and phenotypic rescue reveal that an intact Eyeless protein is necessary for normal eye and brain development in Drosophila.Semantic proximity Read ↗

Regulation of twin of eyeless during Drosophila development.Semantic proximity Read ↗

Pax proteins and eye development.Semantic proximity Read ↗

Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development.Semantic proximity Read ↗

Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless.Semantic proximity Read ↗

The eyeless mutant gene (e) in the Mexican axolotl (Ambystoma mexicanum) affects pax-6 expression and forebrain axonogenesis.Semantic proximity Read ↗

Eye development.Semantic proximity Read ↗

Eye specification in Drosophila: perspectives and implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.