Article
Brain structures of a medaka mutant, el (eyeless), in which eye vesicles do not evaginate.
Brain, behavior and evolution - 1 Jan 2001
Ishikawa Y, Yoshimoto M, Yamamoto N, Ito H, Yasuda T, Tokunaga F, Iigo M, Wakamatsu Y, Ozato K
Abstract excerpt
Eye development and brain structures of a mutant teleost fish were investigated. The el (eyeless) mutation in medaka (Oryzias latipes) is recessive and affects eye formation; in the most severe cases, it results in the absence of eyes. Developmental studies revealed that normal eyeballs are not formed in the el mutant embryos, but small optic cup-like structures differentiate in situ in the walls of the...
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