Article
Regulator of G protein signaling RGS3T is localized to the nucleus and induces apoptosis.
The Journal of biological chemistry - 14 Jul 2000
Dulin N O, Pratt P, Tiruppathi C, Niu J, Voyno-Yasenetskaya T, Dunn M J
Abstract excerpt
RGS3 belongs to a family of the regulators of G protein signaling (RGS). We previously demonstrated that cytosolic RGS3 translocates to the membrane to inhibit G(q/11) signaling (Dulin, N. O., Sorokin, A., Reed, E., Elliott, S., Kehrl, J., and Dunn, M. J. (1999) Mol. Cell. Biol. 19, 714-723). This study examines the properties of a recently identified truncated variant termed RGS3T. Both RGS3 and RGS3T bound to...
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