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Function and regulation of RGS family members in solid tumours: a comprehensive review

3 Nov 2023

Abstract excerpt

G protein-coupled receptors (GPCRs) play a key role in regulating the homeostasis of the internal environment and are closely associated with tumour progression as major mediators of cellular signalling. As a diverse and multifunctional group of proteins, the G protein signalling regulator (RGS) family was proven to be involved in the cellular transduction of GPCRs. Growing evidence has revealed dysregulation of...

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PMID: 37924113
DOI: 10.1186/s12964-023-01334-7

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