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Article

Specificity of RGS10A as a key component in the RANKL signaling mechanism for osteoclast differentiation

19 Sept 2007

Abstract excerpt

Significant progress has been made in studies of the mechanisms by which RANKL induces terminal osteoclast differentiation. However, many crucial details in the RANKL-evoked signaling pathway for osteoclast differentiation remain to be defined. We characterized genes specifically expressed in osteoclasts by differential screening of a human osteoclastoma cDNA library, and found that the regulator of G-protein...

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PMID: 17881498
DOI: 10.1242/jcs.008300

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