Article
Mutational analysis of the PTEN/MMAC1 gene in primary oesophageal squamous cell carcinomas.
Molecular pathology : MP - 1 Dec 1999
Hu Y C, Lam K Y, Tang J C, Srivastava G
Abstract excerpt
AIM: To investigate whether PTEN/MMAC1 mutations play a role in the carcinogenesis of oesophageal squamous cell carcinoma. METHODS: A panel of 33 primary oesophageal squamous cell carcinoma tumour samples and 20 corresponding morphologically normal tissues was examined for mutations in all nine exons of the PTEN/MMAC1 gene by means of polymerase chain reaction single strand conformational polymorphism analysis...
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