Article
[Radiosensitivity on colorectal neoplasms by recombinant adenoviral-mediated wild-type p53 gene].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Aug 2005
Cui Bin-bin, Liu Ming, Zhao Peng, Zhao Jia-hong, Dong Xin-shu
Abstract excerpt
OBJECTIVE: To study the radiosensitization on the cells of colorectal cancer transfected with recombinant adenovirus vector-mediated wild-type p53. METHODS: SW480 cells transfected by wild-type p53 were treated with 4 Gy and 6 Gy radiation. The expression of recombinant adenovirus vector-mediated wild-type p53 gene was detected by Western blotting. The inhibition rate of SW480 cells was examined by MTT, apoptotic...
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