Article
Loss of heterozygosity on chromosome 6p21.2 as a potential marker for recurrence after radiotherapy of human cervical cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2000
Harima Y, Harima K, Sawada S, Tanaka Y, Arita S, Ohnishi T
Abstract excerpt
Cervical carcinomas develop as a result of multiple genetic alterations, and specific alterations lead to specific clinical behavior. However, the effect of such alterations on the recurrence of cervical cancer after radiotherapy remains unknown. Chromosome arm 6p is one of those most frequently involved in a loss of heterozygosity (LOH) in patients with cervical carcinoma. The aim of this study was to identify...
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