Article
Protein expression of p53 and Bcl-2 has a strong correlation with radiation resistance of laryngeal squamous cell carcinoma but does not predict the radiation failure before treatment.
Oncology reports - 1 Jan 2000
Ogawa Takenori, Shiga Kiyoto, Tateda Masaru, Saijo Shigeru, Suzuki Takashi, Sasano Hironobu, Miyagi Taeko, Kobayashi Toshimitsu
Abstract excerpt
To examine what factors can precisely predict the radio-sensitivity or radio-resistance of early stage laryngeal squamous cell carcinomas (LSCC), protein expression of p53, Bcl-2 and Bax and loss of heterozygosity (LOH) at 3p and 9p loci were investigated. From June 1994 through June 1999, specimens of primary tumors were obtained by biopsy from 21 patients diagnosed as early stage LSCC at Miyagi Cancer Center...
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