Article
Genetic alterations on chromosome 17p associated with response to radiotherapy in bulky cervical cancer.
British journal of cancer - 1 Sept 1999
Harima Y, Shirahama S, Harima K, Aoki S, Ohnishi T, Tanaka Y
Abstract excerpt
Chromosome 17 alterations are found in more cancers than those of any other chromosome, and frequently involve the p53 gene on 17p13. The aim of this study was to identify the correlations between the presence of loss of heterozygosity (LOH) and microsatellite instability (MI) on chromosome 17p13 in patients with cervical cancer and the patients' response to radiotherapy. A total of 50 patients were treated with...
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