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Article

The factor V R2 allele: risk of venous thromboembolism, factor V levels and resistance to activated protein C.

Thrombosis and haemostasis - 1 Feb 2000

Luddington R, Jackson A, Pannerselvam S, Brown K, Baglin T

Abstract excerpt

Case-control studies have yielded conflicting results regarding the relative risk of venous thromboembolism associated with the factor V R2 allele. We calculated odds ratios in 581 patients and 469 age-matched controls. The odds ratio for the R2 allele in patients relative to controls was 1.21 (95% CI 0.84 to 1.74). These results do not support the hypothesis that the R2 allele is a risk factor for venous...

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PMID: 10739373

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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