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Article

The factor V gene A4070G mutation and the risk of venous thrombosis.

Thrombosis and haemostasis - 1 Feb 1999

Alhenc-Gelas M, Nicaud V, Gandrille S, van Dreden P, Amiral J, Aubry M L, Fiessinger J N, Emmerich J, Aiach M

Abstract excerpt

The A4070G polymorphism in exon 13 of the factor V (FV) gene, which replaces His by Arg at position 1299 of the B domain, was recently shown to influence circulating FV levels and to contribute to the activated protein C (APC) resistance phenotype. We examined the impact of this polymorphism in a...

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PMID: 10063990

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10063990-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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