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Article

Cysteine 3 is not the site of in vitro palmitoylation on G(salpha).

Biochemical and biophysical research communications - 2 Apr 2000

Scholich K, Yigzaw Y, Patel T B

Abstract excerpt

Several studies have examined the role of palmitoylation of G protein alpha subunits by nonenzymatic in vitro acylation using palmitoyl-CoA. Here, we investigated nonenzymatic palmitoylation of purified G(salpha) in vitro. GDP-bound G(salpha) was stoichiometrically autoacylated on cysteine residue(s) with micromolar concentrations of palmitoyl-CoA. The acylation led to a complete loss of steady-state GTPase...

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Share to GTP-Binding Protein alpha Subunits, Gs

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Source

Identifiers

PMID: 10733916
DOI: 10.1006/bbrc.2000.2400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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