Article
Proteasome involvement in the degradation of the G(q) family of Galpha subunits.
The FEBS journal - 1 Oct 2005
Johansson Bente B, Minsaas Laura, Aragay Anna M
Abstract excerpt
Metabolically unstable proteins are involved in a multitude of regulatory networks, including those that control cell signaling, the cell cycle and in many responses to physiological stress. In the present study, we have determined the stability and characterized the degradation process of some members of the G(q) class of heterotrimeric G proteins. Pulse-chase experiments in HEK293 cells indicated a rapid...
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