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Article

Locus heterogeneity, anticipation and reduction of the chromosome 2p minimal candidate region in autosomal dominant familial spastic paraplegia.

Neurogenetics - 1 Sept 1997

Scott W K, Gaskell P C, Lennon F, Wolpert C M, Menold M M, Aylsworth A S, Warner C, Farrell C D, Boustany R M, Albright S G, Boyd E, Kingston H M, Cumming W J, Vance J M, Pericak-Vance M A

Abstract excerpt

We examined 11 Caucasian pedigrees with autosomal dominant 'uncomplicated' familial spastic paraplegia (SPG) for linkage to the previously identified loci on chromosomes 2p, 14q and 15q. Chromosome 15q was excluded for all families. Five families showed evidence for linkage to chromosome 2p, one to chromosome 14q, and five families remained indeterminate. Homogeneity analysis of combined chromosome 2p and 14q...

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Identifiers

PMID: 10732810
DOI: 10.1007/s100480050014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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