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Article

Refinement of the SPG15 candidate interval and phenotypic heterogeneity in three large Arab families.

Neurogenetics - 1 Nov 2007

Elleuch Nizar, Bouslam Naima, Hanein Sylvain, Lossos Alexander, Hamri Abdelmadjid, Klebe Stephan, Meiner Vardiella, Birouk Nezha, Lerer Israela, Grid Djamel, Bacq Delphine, Tazir Meriem, Zelenika Diana, Argov Zohar, Durr Alexandra, Yahyaoui Mohamed, Benomar Ali, Brice Alexis, Stevanin Giovanni

Abstract excerpt

Hereditary spastic paraplegia (HSP) type 15 is an autosomal recessive (AR) form of complicated HSP mainly characterized by slowly progressive spastic paraplegia, mental retardation, intellectual deterioration, maculopathy, distal amyotrophy, and mild cerebellar signs that has been associated with the Kjellin syndrome. The locus for this form of HSP, designated SPG15, was mapped to an interval of 19 cM on...

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Source

Identifiers

PMID: 17661097
DOI: 10.1007/s10048-007-0097-x

Genes

GPHN
SPG21
SPG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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