Article
Dissecting the locus heterogeneity of autism: significant linkage to chromosome 12q14.
Molecular psychiatry - 1 Apr 2007
Ma D Q, Cuccaro M L, Jaworski J M, Haynes C S, Stephan D A, Parod J, Abramson R K, Wright H H, Gilbert J R, Haines J L, Pericak-Vance M A
Abstract excerpt
Autism is a common neurodevelopmental disorder with a significant genetic component and locus heterogeneity. To date, 12 microsatellite genome screens have been performed using various data sets of sib-pair families (parents and affected children) resulting in numerous regions of potential linkage across the genome. However, no universal region or consistent candidate gene from these regions has emerged. The use...
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