Article
H19 and IGF-2 allele-specific expression in hepatoblastoma.
British journal of cancer - 1 Feb 2000
Ross J A, Radloff G A, Davies S M
Abstract excerpt
Patterns of allele-specific expression of H19 and insulin-like growth factor-2 (IGF-2) were examined in tissue obtained from 30 children diagnosed with hepatoblastoma. All informative tumours demonstrated monoallelic expression of H19. In contrast, variable patterns of allele-specific expression of IGF-2 were seen in tumours from children of different ages.
Topics
- Alleles
- Base Sequence
- Child
- Child, Preschool
- DNA Primers
- Female
- Hepatoblastoma
- Humans
- Infant
- Infant, Newborn
- Insulin-Like Growth Factor II
- Liver Neoplasms
- Male