Article
Association of antiphosphatidylserine/prothrombin autoantibodies with HLA class II genes.
Arthritis and rheumatism - 1 Mar 2000
Bertolaccini M L, Atsumi T, Caliz A R, Amengual O, Khamashta M A, Hughes G R, Koike T
Abstract excerpt
OBJECTIVE: To investigate the associations between HLA class II genes and antiphosphatidylserine/prothrombin antibodies (aPS/PT) in a group of British caucasoid patients with antiphospholipid antibodies (aPL). METHODS: This study included 82 patients with aPL. IgG aPS/PT were detected in sera using enzyme-linked immunosorbent assays. HLA-DQB1, DQA1, and DRB1 genotypes were determined by polymerase chain reaction...
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