Article
HLA class II alleles associations of anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosus.
Lupus - 1 Jan 2000
Galeazzi M, Sebastiani G D, Tincani A, Piette J C, Allegri F, Morozzi G, Bellisai F, Scorza R, Ferrara G B, Carcassi C, Font J, Passiu G, Smolen J, Papasteriades C, Houssiau F, Nebro A F, Ramon Garrido E D, Jedryka-Goral A, Marcolongo R
Abstract excerpt
The objective of this study was to determine the HLA class II associations of the anticardiolipin (aCL) and anti-beta2GPI (abeta2GPI) antibodies in a large series of European patients with systemic lupus erythematosus (SLE). A cohort of 577 European SLE patients was enrolled. aCL and abeta2GPI were measured by ELISA methods. Molecular typing of HLA-DRB1, DRB3, DRB4, DRB5, DQA1 and DQB1 loci was performed by the...
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