Article
Genetics of antiphospholipid syndrome.
Current rheumatology reports - 1 Dec 2004
Horita Tetsuya, Merrill Joan T
Abstract excerpt
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by recurrent arterial or venous thrombosis or fetal loss and the presence of antiphospholipid antibodies (aPL). Genetic factors are thought to play a role in the susceptibility to APS. Similar to many other polygenic autoimmune diseases, human leukocyte antigen associations have been reported. The genetics of b(2)-glycoprotein I, one of the...
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