Article
Anti-cofactor autoantibodies in systemic lupus erythematosus: prevalence, clinical and HLA class II associations.
Immunological investigations - 1 Jan 2008
Sebastiani Gian Domenico, Morozzi Gabriella, Bellisai Francesca, Fineschi Irene, Bacarelli Maria Romana, Simpatico Antonella, Font Josep, Cervera Ricard, Houssiau Frederic, Fernandez-Nebro Antonio, De Ramon Garrido Enrique, De Pità Ornella, Smolen Josef, Galeazzi Mauro
Abstract excerpt
The aim of our study was to evaluate the clinical and HLA-class II allele associations of some anti-cofactor antibodies in a homogeneous group of European patients with SLE. One hundred thirty-six patients with SLE, fulfilling four or more of the ACR 1997 revised criteria for the classification of the disease, coming from 7 European countries, were enrolled consecutively. Anti-prothrombin (anti-PT), anti-annexin...
Topics
- Adult
- Alleles
- Autoantibodies
- Female
- Gene Frequency
- Genes, MHC Class II
- Humans
- Lupus Erythematosus, Systemic
- Male