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Article

HLA class II alleles and genetic predisposition to the antiphospholipid syndrome.

Autoimmunity reviews - 1 Oct 2003

Domenico Sebastiani Gian, Minisola Giovanni, Galeazzi Mauro

Abstract excerpt

The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antiphospholipid antibodies (aPL). Its etiology is linked to genetic predisposition, which is accounted for, at least in part, by genes of major histocompatibility complex (HLA system). The association of APS with human leukocyte antigen (HLA) alleles is a consequence of the association of aPL with HLA alleles. Some HLA...

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Identifiers

PMID: 14550881
DOI: 10.1016/s1568-9972(03)00068-5

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