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Article

Peptide analogs from E-cadherin with different calcium-binding affinities.

The journal of peptide research : official journal of the American Peptide Society - 1 Mar 2000

Yang W, Tsai T, Kats M, Yang J J

Abstract excerpt

Cadherins are a family of calcium-dependent cell-surface proteins that are fundamental in controlling the development and maintenance of tissues. Motif B of E-cadherin seems to be a crucial calcium-binding site as single point mutations (D134A and D134K) completely inactivate its adhesion activity. We analyzed peptide models corresponding to motif B (amino acids 128-144) as well as selected mutations of this...

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Identifiers

PMID: 10727102
DOI: 10.1034/j.1399-3011.2000.00169.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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