Article
The crystal structure of annexin A8 is similar to that of annexin A3.
Journal of molecular biology - 4 Feb 2005
Réty Stéphane, Sopková-de Oliveira Santos Jana, Dreyfuss Lise, Blondeau Karine, Hofbauerová Katerina, Raguénès-Nicol Céline, Kerboeuf Daniel, Renouard Madalena, Russo-Marie Françoise, Lewit-Bentley Anita
Abstract excerpt
Annexin A8 is a relatively infrequent and poorly studied member of this large family of calcium-binding and membrane-binding proteins. It is, however, associated with a specific disease, acute promyelocytic leukemia. We have solved its three-dimensional structure, which includes a moderately long and intact N terminus. The structure is closest to that of annexin A3 and highlights several important regions of...
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