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Article

Role of calcium-binding sites in calcium-dependent membrane association of annexin A4.

Bioscience, biotechnology, and biochemistry - 1 Jan 2015

Arii Yasuhiro, Butsusihta Kohei, Fukuoka Shin-Ichi

Abstract excerpt

Annexin A4 (Anx4) is a cytosolic calcium-binding protein with four repeat domains, each containing one calcium-binding site (CBS). The protein interacts with the phospholipid membrane through the CBS-coordinated calcium ion, although the role of each CBS in the calcium-dependent association is unclear. To determine the role of each CBS, 15 CBS-abolished variants were produced in various combinations by...

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Source

Identifiers

PMID: 25649809
DOI: 10.1080/09168451.2014.1003131

Genes

CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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