In vivo regulation of cell death by embryonic (pro)insulin and the insulin receptor during early retinal neurogenesis

Abstract excerpt

Programmed cell death is an established developmental process in the nervous system. Whereas the regulation and the developmental role of neuronal cell death have been widely demonstrated, the relevance of cell death during early neurogenesis, the cells affected and the identity of regulatory local growth factors remain poorly characterized. We have previously described specific in vivo patterns of apoptosis...

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