Article
Differential and tissue-specific regulation of (pro)insulin and insulin-like growth factor-I mRNAs and levels of thyroid hormones in growth-retarded embryos.
Growth regulation - 1 Jun 1996
Serna J, González-Guerrero P R, Scanes C G, Prati M, Morreale G, de Pablo F
Abstract excerpt
The control of embryonic growth in vertebrates appears to rely on the orchestrated action of several families of growth factors and hormones. The contribution of insulin-like growth factor (IGF-I) to prenatal growth regulation is better established in mammals than in other vertebrate species. The status of (pro)insulin gene product(s) in the pancreas and non-pancreatic tissues may be another important...
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