Article
Differential and tissue-specific regulation of (pro)insulin and insulin-like growth factor-I mRNAs and levels of thyroid hormones in growth-retarded embryos.
Growth regulation - 1 Jun 1996
Serna J, González-Guerrero P R, Scanes C G, Prati M, Morreale G, de Pablo F
Abstract excerpt
The control of embryonic growth in vertebrates appears to rely on the orchestrated action of several families of growth factors and hormones. The contribution of insulin-like growth factor (IGF-I) to prenatal growth regulation is better established in mammals than in other vertebrate species. The...
Topics
- Animals
- Chick Embryo
- Fetal Growth Retardation
- Gene Expression Regulation, Developmental
- Growth Hormone
- In Situ Hybridization
- Insulin-Like Growth Factor I
- Oligonucleotide Probes
- Phenotype
- Polymerase Chain Reaction
- Proinsulin
- RNA, Messenger
- Radioimmunoassay
- Thyroid Hormones
- Thyroxine
- Triiodothyronine