Regulation of apoptosis in the bovine blastocyst by insulin and the insulin‐like growth factor (IGF) superfamily

Abstract excerpt

Insulin and the insulin-like growth factors, IGF-I and IGF-II, have been reported to exert a mitogenic effect on the preimplantation mammalian embryo. Furthermore, it has been proposed that loss of imprinting of the insulin-like growth factor II receptor gene and the consequent over-production of IGF-II may be involved in the aetiology of the Enlarged Offspring Syndrome, which occurs as an artefact of in vitro...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Syndromes and Imprinting
• Share to Prenatal Screening and Diagnostics
• Share to Reproductive Biology and Fertility