Article
Anti-Apoptotic Action of Insulin-Like Growth Factor-I During Human Preimplantation Embryo Development
1 Nov 2000
Abstract excerpt
Insulin-like growth factor I (IGF-I) has been shown to increase the proportion of embryos forming blastocysts and the number of inner cell mass cells in human and other mammalian preimplantation embryos. Here we examined whether the increased cell number resulted from increased cell division or decreased cell death. Normally fertilized, Day 2 human embryos of good morphology were cultured to Day 6 in glucose-free...
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