Article
Strand symmetry around the beta-globin origin of replication in primates.
Molecular biology and evolution - 1 Mar 2000
Francino M P, Ochman H
Abstract excerpt
Certain mutations are known to occur with differing frequencies on the leading and lagging strands of DNA. The extent to which these mutational biases affect the sequences of higher eukaryotes has been difficult to ascertain because the positions of most replication origins are not known, making it impossible to distinguish between the leading and lagging strands. To resolve whether strand biases influence the...
Topics
- Animals
- Base Composition
- DNA Mutational Analysis
- DNA Replication
- Globins
- Molecular Sequence Data
- Mutation
- Phylogeny
- Primates
- Replication Origin