Strand symmetry of mutation rates in the beta-globin region.

doi:10.1007/BF02102861

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Article

Strand symmetry of mutation rates in the beta-globin region.

Journal of molecular evolution - 1 Oct 1991

Bulmer M

Abstract excerpt

It has been suggested that there may be inequalities in the types of substitution on the two DNA strands (in particular, in the frequencies of transversions from R to Y and from Y to R) due to a higher error rate on the lagging than the leading strand during replication. Reexamination of 11 kb of...

Topics

Animals
Base Composition
Biological Evolution
DNA Mutational Analysis
DNA Replication
Globins
Humans
Mutation
Primates

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