Article
New dopamine receptor, D2(Longer), with unique TG splice site, in human brain.
Brain research. Molecular brain research - 10 Mar 2000
Seeman P, Nam D, Ulpian C, Liu I S, Tallerico T
Abstract excerpt
Brain dopamine receptor agonists alleviate the signs of Parkinson's disease, while dopamine receptor antagonists alleviate hallucinations and delusions in psychosis. The dopamine type 2 receptor (or D2) is blocked by antipsychotic drugs, including even the "atypical" drugs such as clozapine or remoxipride, in direct relation to their clinical potencies. Compared to the long form of the D2 receptor (D2(Long)), the...
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