Article
Both splicing variants of the dopamine D2 receptor mRNA are up-regulated by antipsychotic drugs.
Neuroscience letters - 5 Feb 1993
Buckland P R, O'Donovan M C, McGuffin P
Abstract excerpt
We have investigated the effects of antipsychotic drugs on the expression of the two dopamine D2 receptor splicing variants using multiprobe oligonucleotide solution hybridisation. Both long and short mRNA variants were increased in abundance by approximately 2-fold by both haloperidol and loxapine after 32 days drug administration.
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