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Article

Endogenous and exogenous factors contributing to the surface expression of HLA B27 on mutant APC.

Human immunology - 1 Feb 2000

Purcell A W, Kelly A J, Peh C A, Dudek N L, McCluskey J

Abstract excerpt

We have examined the expression of HLA B*2705 in the mutant cell line 721.220, which lacks endogenous HLA A and B alleles and expresses a defective tapasin molecule. Several peptide sensitive mAbs distinguish between HLA B*2705 expressed on the surface of 721.220 cells (B27.220) and 721.220 cells co-transfected with human tapasin (B27.220.hTsn). This differential staining defines subtle differences in the...

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PMID: 10717804
DOI: 10.1016/s0198-8859(99)00139-1

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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