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Article

Isolating aging mutants: a novel method yields three strains of the nematode Caenorhabditis elegans with extended life spans.

Mechanisms of ageing and development - 7 Feb 2000

Yang Y, Wilson D L

Abstract excerpt

We designed a novel procedure for the isolation of mutant strains with significantly increased life spans in the nematode Caenorhabditis elegans. This procedure involves using heat-shock to screen a large number of animals and isolate a few which are more resistant to heat-shock stress. From the heat-shock-resistant animals, three mutant strains, HG25, HG96, and HG246, all exhibiting increased life span, were...

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PMID: 10708258
DOI: 10.1016/s0047-6374(99)00100-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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