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Article

Production of age-synchronous mass cultures of Caenorhabditis elegans.

Journal of gerontology - 1 Jul 1994

Fabian T J, Johnson T E

Abstract excerpt

Methods are described for culturing large populations of age-synchronous Caenorhabditis elegans throughout the adult life span. Contamination of adult populations by progeny was prevented by constructing double-mutant strains that produce progeny at a frequency of less than .005 per adult at the nonpermissive temperature (25.5 degrees C). Of four double-mutant strains that we have characterized, three have...

Topics

Aging
Animals
Breeding
Caenorhabditis elegans
Cholesterol
Culture Media
Eggs
Escherichia coli
Fertility
Genotype
Longevity
Mutation
RNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Bacterial

RNA, Ribosomal

Survival Rate

Source

Identifiers

PMID: 7516947
DOI: 10.1093/geronj/49.4.b145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7516947-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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