Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing.

doi:10.1242/dev.124.10.1919

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing.

Development (Cambridge, England) - 1 May 1997

de Celis J F, Bray S, Garcia-Bellido A

Abstract excerpt

The veins in the Drosophila wing have a characteristic width, which is regulated by the activity of the Notch pathway. The expression of the Notch-ligand Delta is restricted to the developing veins, and coincides with places where Notch transcription is lower. We find that this asymmetrical distr...

Topics

Animals
Basic Helix-Loop-Helix Transcription Factors
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Genes, Insect
Insect Proteins
Intracellular Signaling Peptides and Proteins
Membrane Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Receptors, Notch

Repressor Proteins

Signal Transduction

Veins

Wings, Animal

Source

Open in PubMed

Identifiers

PMID: 9169839
DOI: 10.1242/dev.124.10.1919

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9169839-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing.PMID 9169839Read ↗

Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing.Semantic proximity Read ↗

Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs.Semantic proximity Read ↗

Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis.Semantic proximity Read ↗

The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development.Semantic proximity Read ↗

Roles of the Notch gene in Drosophila wing morphogenesis.Semantic proximity Read ↗

Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc.Semantic proximity Read ↗

Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch.Semantic proximity Read ↗

Notch signaling directly controls cell proliferation in the Drosophila wing disc.Semantic proximity Read ↗

Different spatial and temporal interactions between Notch, wingless, and vestigial specify proximal and distal pattern elements of the wing in Drosophila.Semantic proximity Read ↗

Blistered: a gene required for vein/intervein formation in wings of Drosophila.Semantic proximity Read ↗

A novel interaction between hedgehog and Notch promotes proliferation at the anterior-posterior organizer of the Drosophila wing.Semantic proximity Read ↗

Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.