Article
Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing.
Development (Cambridge, England) - 1 May 1997
de Celis J F, Bray S, Garcia-Bellido A
Abstract excerpt
The veins in the Drosophila wing have a characteristic width, which is regulated by the activity of the Notch pathway. The expression of the Notch-ligand Delta is restricted to the developing veins, and coincides with places where Notch transcription is lower. We find that this asymmetrical distribution of ligand and receptor leads to activation of Notch on both sides of each vein within a territory of...
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