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Article

Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development.

Development (Cambridge, England) - 1 Dec 2003

Giraldez Antonio J, Cohen Stephen M

Abstract excerpt

Tissue growth during animal development depends on the coordination of cell proliferation and cell death. The EGF-receptor/MAPK, Hedgehog, Dpp, Wingless (Wg) and Notch signaling pathways have been implicated in growth control in the developing Drosophila wing. In this report, we examine the effects of Notch and Wg on growth in terms of cell proliferation and cell survival. Reduction of Wg signaling impaired...

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Share to Cell Survival
Share to Embryo, Nonmammalian
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins

Share to Receptors, Notch

Share to Wings, Animal

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Source

Identifiers

PMID: 14660542
DOI: 10.1242/dev.00904

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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