Article
Melanocortin 3 receptor (MC3R) gene variants in extremely obese women.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Feb 2000
Li W D, Joo E J, Furlong E B, Galvin M, Abel K, Bell C J, Price R A
Abstract excerpt
OBJECTIVE: Following several reports of linkage of obesity related phenotypes to human chromosome 20q we sought to determine whether variations of the melanocortin 3 receptor (MC3R) gene are associated with obesity. DESIGN: We screened the MC3R gene coding region and approximately 2 kb of 5' and 3' flanking sequences for DNA variants in unrelated extremely obese women and average weight controls using polymerase...
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