Article
Impact of the Peroxisome Proliferator Activated Receptor gamma2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Feb 2000
Meirhaeghe A, Fajas L, Helbecque N, Cottel D, Auwerx J, Deeb S S, Amouyel P
Abstract excerpt
OBJECTIVE: The Pro12Ala polymorphism of the Peroxisome Proliferator Activated Receptor gamma2 (PPARgamma2) gene has been inconsistently associated with body mass index variations and non-insulin-dependent diabetes mellitus (NIDDM). We investigated the impact of this polymorphism on obesity markers, lipid and glucose variables in a sample of French subjects and evaluated its possible role in the onset of NIDDM....
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